Does Zyban Really Work?

Does Zyban really work?Thinking of using Zyban to increase your chances of giving up smoking. Quitting smoking is a commendable choice, but you have to be careful how you go about it. The health benefits of quitting cannot be overlooked, and begin the day you quit, so it’s important to get started quitting right away. But jumping into using something has powerful as Zyban is not a wise move.

What It Is
Zyban is the trademarked name for bupropion a smoking cessation drug. It is manufactured by the pharmaceutical corporation GlaxoSmithKline, commonly abbreviated to GSK. It has been around since before 2007 and has sold well ever since. It first came about as an anti-depressant and later it was found to have success in helping people quit smoking. It is a different drug entirely from varenicline, which is the generic name of Chantix.

Zyban boasts that it is nicotine-free, and that it doesn’t include many of the substances used in typical stop smoking products. This is an important characteristic, and many people believe that you should not cure something with itself. When you use a nicotine-containing product you aren’t really giving up the thing you’re addicted to, just the harmful effects of inhaling the smoke and other substances in cigarettes. At the end of the day you’re still addicted to nicotine, and could suffer a relapse.

With a product that contains no nicotine you’re giving up nicotine and cigarettes both, so it can be harder to do. You will definitely need some powerful help with this task, and that’s where something like Zyban or other nicotine-free products hope to step in.

Side Effect vs Withdrawal Symptoms
It can be hard to decipher the difference between the cravings and withdrawal symptoms of quitting smoking, from the side effects of taking drugs like Zyban. You may have depressed thoughts that even border on suicidal when you quit smoking, and perhaps Zyban just lowers them further.

The Role of the FDA
Many people think that the Food and Drug Administration is in place to prevent these sorts of drugs from being released, but all they’ve done so far is to force the makers of Zyban to prominently display the side effect warnings. This makes them look just like the packs of cigarettes you’re trying to quit.

Apparently the FDA will allow medications like these to pass, and then will assess the damage after the public starts using it. If there are a lot of negative side effects, they’ll force pharmaceutical companies to put warning labels on them, and if they cause too many deaths they’ll force a recall of the drug.

The side effects are for real:

User Feedback and Testing
Many people that have tried Zyban say that they’ve been able to successfully stop smoking, and stay that way for years. GSK has stated that compared to placebo, Zyban is twice as effective. Only a quarter of the people using Zyban reported an increased urge to smoke, compared with half of those on the placebo. Additionally, those that took the placebo were more likely to experience mood swings while quitting. This could be attributed to the antidepressant roots of Zyban.

Stop Smoking Tips
The best way to stop smoking is using a multi-angled approach. The problem with these sort of drugs is that it creates the illusion that all you need to do in order to be successful is just pop a pill. But this is rarely the case because the habit of smoking affects you on many different levels. It is not just the addiction to nicotine on a physical level, it’s also the psychological things about smoking that illness, as well as the habit of simple things like always having a cigarette in your finger.

So in your treatment approach make sure you try to think about all of these different angles and have something in place, whether it be a support group to talk about what you’re going through, or a healthy substitute like chewing gum instead of having a cigarette in your mouth. All of this would be in addition to whatever you’re using to combat the nicotine cravings.

Final Zyban Review

So while this make Zyban much more effective than Chantix, does this mean that this is the prescription drug of choice for those looking to quit smoking? The fact remains that there are still plenty of negative side effects that come with Zyban, and they’re very similar as well. Having suicidal tendencies is not a good thing, especially when you’re trying to quit smoking an already stressed about that. But since it is more effective in clinical trials compared with placebo, it’s probably better to go with Zyban Chantix if your doctor has given you the choice.

Our Recommendation
We recommend using Zyban only as a last resort. There are so many drug-free ways to quit, including support groups, all-natural remedies, going cold turkey, audio courses, books, and more that there is no need to resort to using medication with so many possible negative side effects associated with it.

What do you think? Does Zyban work or not?


{ 3 comments… read them below or add one }

Phyllis DeFalco July 8, 2013 at 11:10 pm

Here is the long and the short of it again from a medical standpoint. Your success with this product is measured directly by how you are personally addicted to smoking. Are you chemically addicted or are you orally addicted? Big difference. This product works well as I have an aunt using it and I also have another cousin using E cigs. This has been successful for both because one cures a chemical addiction while the other cures the oral fixated person who is not so chemically addicted so experiment with both kinds of processes and find out what works for you.


Andres Vargas July 22, 2013 at 3:03 pm

What’s interesting here is the lack of explanation as to how this particular drug works. For example we know that anti-depressant medication works by inhibiting and activating the neurons in the brain responsible for controlling the release of dopamine and serotonin. But what are the drugs that supposedly help you quit smoking supposed to be doing? Are they somehow mimicking the signal you would be getting from having a cigarette? I don’t know, and a cursory investigation doesn’t yield much new information. I am deeply sceptical about any drug that does not make its process transparent. Wouldn’t i be just as good to chew nicotine gum?


RLG August 4, 2013 at 10:32 am

I tried Zyban several years ago for about 2 weeks. I was left so depressed by taking the medication that I had to stop using it. It was expensive as my insurance company wouldn’t cover the cost, go figure. I guess they would rather me keep smoking to have additional medical charges from additional doctor visits. It didn’t work for me as I had to quit taking it, but it may work good for others. I didn’t like the feeling it left me with. Depressed, nervous and even nightmares.


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