Does Penetrex Cream Really Reduce Pain & Inflammation?

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Penetrex is an anti-inflammatory treatment that is designed to help with a myriad of disorders and conditions, and claims to have a large following of happy customers. They’ve got the social proof to back it up, and a guarantee that their product works, so is this the real deal or is there something more to this that’s worth looking into?


What is Penetrex?

Joint Pain

When you suffer from pain in your shoulders, back, neck, knees, feet or any other part of your body you look for a product that will give you the fastest, best relief. Penetrex Pain Relief Therapy is a great product for reducing inflammation that causes pain.


This is an anti-inflammatory cream that provides fast, strong and long-lasting relief from various types of pain. It is ideal for joint pain. There are several different types of anti-inflammatory creams on the market so if one doesn’t work it is worth trying another.

Penetrex Can Be Used In Conjunction With Other Treatments


The cream can be applied anywhere you experience pain. It can be used on the neck, back, feet, hands, and legs to name a few areas for use. Penetrex can be used on its own or in conjunction with other pain-relieving aids such as:

  • Heating Pads
  • Back Pain Massagers
  • Neuropathy Socks
  • Sciatica Cushions
  • Carpal Tunnel Braces
  • Tennis Elbow straps
  • Ice Packs
  • Bursitis Braces
  • Fibromyalgia Supplements
  • Arthritis gloves
  • Arthritis wraps
  • Tendonitis Supports
  • Knee Braces

And other pain-relieving aids. People from all over the world have discovered this cream. It has become a very popular pain relief therapy.

What Are the Main Ingredients in Penetrex?


Penetrex contains several clinically proven ingredients. Some of the main ingredients in Penetrex are:

  • Arnica
  • Glucosamine
  • MSM (DMS02)
  • Boswellia Serrata & Vitamin B6 (Pyridoxine)
  • Choline
  • Cetyl Myristoleate


  • This product also contains a vanishing scent, is non-greasy, does not stain clothing, skin or upholstery.


  • It is Paraben Free and has never been tested on animals.

The formulation of the product focuses on the root cause of most pain which is inflammation. It addresses the problem of pain, it does not mask it. The product contains a pharma-grade penetration enhancer which enables the ingredients to penetrate deep into the areas that are affected. This product does not contain any animal by-products and is Vegan and Kosher. Penetrex is 100% U.S.A. made.

How Long Does Pain Relief Last With Penetrex?

Pain Relief


Due to the fact that the cream contains a pharma-grade penetration enhancer, the formula works deep into the affected areas. This results in strong, quick and long lasting pain relief.

This product does not burn the skin or have a strong smell, as it absorbs quickly into the skin.

As some people have a higher pain tolerance than others, the length of time you experience pain relief will vary from person to person. However, overall you can expect pain relief to last for an extended period of time.

This product was voted #1 Best Overall Muscle Rub for the year 2019 by Business Insider.

Is Penetrex a Safe Product?

The product does not contain any addictive ingredients. It does not contain any:

  • Steroids
  • NSAIDs
  • Drugs
  • Parabens

Where Can I buy Penetrex and How Much Does It Cost?

Buy Penetrex

There have not been any reports of recurring issues in the 2 million-plus jars sold to date.

You can buy this product  directly from their website at offers half price shipping on all orders. Orders are processed and shipped within 1 business day via USPS 1st Class Mail International.

They also offer a 100% money back guarantee. Prices from are as follows:

  • Penetrex 2 ounce – $18.98
  • Penetrex 3 ounce roll-on – $25.95
  • Penetrex 4 ounce $34.95
  • Penetrex Bundle – Includes 2 oz., 4 oz, and roll-on for $69.95
  • Penetrex 3 pack of 4 oz size – $97.50
  • Penetrex 6 pack of 2 oz size – $99.00

Penetrex also ships to Canada daily. 

You can purchase it on for $18.95 for a 2 ounce jar with free shipping for Amazon Prime members and also on

You can also buy Penetrex at Walmart in the United States and Canada.

Prices at these locations seem to be somewhat higher than the product website and Amazon. In the near future Penetrex will be available for purchase at Walgreens and CVS Pharmacy.

Customer Reviews


Penetrex has received a 4.2 out of 5 star rating overall. 69% of customers have rated this product 5 out of 5 stars.

One customer stated her doctor was the one who told her about Penetrex for her severe bursitis and was very surprised how well it really did work.

Another 81-year-old woman with severe arthritis has been using Penetrex for over seven years on her hips and shoulders and was so impressed at how well it worked for her that she recommends it to everyone she knows.

Another Penetrex user describes it as the Miracle Cream from Heaven, and uses for foot pain and inflammation.

Other customer testimonials include: 

  • Yeah, its that good. If you have joint or muscle pain, this stuff is a must have!
  • Very good product that really takes the edge off of pain
  • Works great for carpal tunnel and back and neck injuries!
  • Doctor Recommended
  • I would have sold my soul for this relief
  • This stuff really does work!
  • Boom Pow – Penetrex rubs on easily and does well for pain relief
  • Works for me – Fibromyalgia, Osteoarthritis, Tendinosis
  • Debilitating nerve pain relief


When you read all the customer reviews and testimonials it makes you want to run right out and buy some to keep on hand in case you experience these types of pain.



We would highly recommend trying Penetrex if you suffer from pain caused by an accident or if you have ongoing pain issues like:

  • arthritis
  • bursitis
  • carpal tunnel
  • osteoporosis
  • fibromyalgia

or any other debilitating ailment.

The majority of customer reviews indicate that this product works well and would be repeat customers and would recommend this product to family and friends. Keep in mind that for some types of pain OTC products that are taken internally can be beneficial as well.

Overall #1

As this product was rated the #1 Overall Muscle Rub for the year 2019 by Business Insider this is a very good indication that this product works well and is highly regarded.

Many of the customer reviews stated that their doctors recommended this product for certain pain ailments they had. This proves there has been a lot of positive feedback regarding this product in the medical profession.

Try the 2 oz. size to start with and if it works for you, there are many other purchase options for this product. There are even bundle deals that can save you money.

Let us know what your experience with Penetrex is.



5,531 Customer Reviews on “Does Penetrex Cream Really Reduce Pain & Inflammation?

  1. i have 2 knees that qualify for knee replacement but i’m too chicken and i feel too young (51) for surgery yet. near bone on bone w/ arthritis. was always disappointed after buying stuff to help. but took another chance on penetrex and was amazed that it worked so well. when i can’t stand to stand on my feet anymore because of the pain, i put penetrex on and it takes the pain from 7-8 to about a 4 in about 15 min. even though the pain is bad enough to cause a limp, i have to live very frugally so i usually try to save money by using it 1/day. lasts for about 2-4 hours. can get up and keep going, which is what we are all looking for. maybe it doesn’t work for everyone but w/ so many great reviews from so many people, it has to be pretty effective. so grateful for this product!

  2. One of my recurring pain areas in my back is in an area I cannot reach at all (between the shoulder blades), if my husband is not available to rub it in, I have to use a rubber spatula to apply Penetrex to that spot so it doesn’t get massaged in at all. And it still works!
    Also, massaging in other types of pain relief creams or ointments NEVER had even close to the effectiveness that Penetrex does. So it’s really, REALLY not the massage that does it!

  3. My husband says it doesn’t work for him either, but for me? It’s works better than any other cream I’ve ever tried an even Rx painkillers- so much so, I no longer need to take them.

  4. YES! I use it for multiple types of nerve & muscle pain and IT WORKS.
    I have sciatica, cubital tunnel syndrome, myofascial trigger points (muscle “knots”), and long-term lower back, leg, & foot pain due to a motion coordinated disorder and I have tried every pain cream/ointment that exists. Most of them did not help or only helped a little- Penetrex is like some kind of “miracle” cream. I know it sounds too good to be true, but in minutes after applying it my pain starts to subside.
    It was recommended to me by my best friend, who suffers from even more serious injuries/chronic pain issues than I do, and I was skeptical too…until I tried it. Now, I am NEVER without it.

  5. I have sciatica, cubical tunnel syndrome, myofascial trigger points, and long term back, feet, and leg pain issues that are a result of being dyspraxic.
    I use penetrex and it works GREAT! I even rub it on my temples to help with tension headaches.
    It was recommended by my best friend, who has pain & numbness from permanent spinal cord injury, spinal stenosis, needing disc replacement/fusion surgery (has a permanent titanium plate in her neck) as well as from having cubical tunnel syndrome so bad she required surgery for it.
    I have tried every other kind of pain cream/ointment that exists and NOTHING even comes close to Penetrex’s effectiveness. It allowed me to stop taking opioid painkillers and now if I need any it’s strictly OTC.

  6. I’ve used to stuff twice now. Will use it again.

    I messed my shoulder up painting the house a few months ago – one of those injuries one isn’t even aware of until a day or two later. Ache and discomfort arrived, and the next day I couldn’t raise my arm without wincing. In description it felt sort of as if rubber bands were being dragged over a jagged edge, catching and snapping loose. Everyday tasks like making the bed, putting on a shirt, even driving/shifting were new experiences in exquisite pain. Getting to sleep was difficult as simply trying to roll over was a chore. After another day or two I went to the store and purchased a sling and, on a whim, some Penetrex.

    The stuff didn’t provide any immediate relief whatsoever. It doesn’t even do what some of the popular heat rubs do; no sensation at all… but I used it per the directions, three or four times a day, and would wake up each day feeling less pain and with gained range of movement.

    It’s realized the sling played a role, but I never really stopped using the arm and wore the sling only when out and about; Letting the limb hang was painful in itself and holding it up was tiresome and made me look silly.

    At any rate… full, speedy recovery

    Skip ahead to this past week.

    I’ve been sitting behind a keyboard quite a bit lately – more so than usual – on a crummy office chair. I’m not sure what the diagnosis would have been had I went to the doctor, but from what I’ve read, sciatica and/or bursitis seem to fit. Same as with the shoulder – pain, this time at the hip and upper side of thigh – set in and progressively worsened.

    Walking was possible so long as no sudden stops or abrupt course corrections were called for… but they always are. Climbing steps proved a bit more difficult. If trying to carry or push something of only moderate heft, it just plain hurt. Let’s not even mention yard work. There were certain angles I’d have to avoid placing the leg at… and again, getting to sleep was hindered and pressing the clutch pedal made driving unpleasant.

    Just like before, Penetrex was used (second purchase; completely used the last on the shoulder)… and just like before, feeling fine after a few days.


    I’m not going to swear to anyone the stuff’s a miracle ointment that’ll treat any ailment… and even if it’s effectiveness were a bonafide fact, there would certainly still be limitations to what ailments it can treat.

    All I can say is that I’m sold on it.

    Give it a chance to do what it claims it does. One application isn’t enough.


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