Does Penetrex Really Work?

Does Penetrex Really Work?
2.5 (50.48%) 1723 vote[s]

Does Penetrex work?Penetrex is an anti-inflammatory treatment that is designed to help with a myriad of disorders and conditions, and claims to have a large following of happy customers. They’ve got the social proof to back it up, and a guarantee that their product works, so is this the real deal or is there something more to this that’s worth looking into?

If you’ve got general aches and pains you’re probably not too keen on the idea of taking an aspirin or other pain killer every day for relief. A much better alternative would be to take something that is all natural and that’s topical so that it can work at the source rather than going through the entire bloodstream. This way you can use it as needed, and only where you need it. Since most of what it treats only happens on occasion, it makes it a handy product to have around.

The Claim
The makers of Penetrex claim that it can help with things like plantar fasciitis, arthritis, golfer’s elbow, tennis elbow, carpal tunnel syndrome, tendinitis, bursitis, sciatica, shin splints, fibromyalgia, neuropathy, and others. It’s quite a laundry list of things that can ail you as you get older, and this seems to be marketed toward the baby boomer crowd. They even claim that their product is often on backorder, which might seem like a marketing ploy, but with all of the positive feedback they might actually be telling the truth.

The Hype
The hype on this is twofold, both in the number of people that have tried it and says that it works, and the long list of things it’s been said to help treat. Usually when you find a product like this that says it treats just about anything, it’s a hoax or a scam. But with so many people vouching for it, there’s little reason to believe that it’s anything but legit. It’s always good to try to do some research on a product, but when it’s all natural, priced right, and has heaps of authentic feedback it’s OK to go with the flow.

The Cost
A jar of Penetrex is just $20 on Amazon and ships free if you get your order over $25. This is another thing that it’s got going for it, they haven’t inflated the price, even with so many people ordering it that they occasionally run out. In a free market economy with the law of supply and demand, and shadier manufacturer might have quietly upped the price the more popular this became. At this price it’s almost a no-brainer, and something that most people will try out, especially since you can get your money back if it doesn’t work for you.

The Commitment
This is the part that most people like about it, you only use it when you need it, making it very convenient, and not something you have to remember to take every day. It’s easy enough to remember to take it when the pain starts acting up. Users say that it goes to work almost instantly, so there’s no need to take it before you feel the pain. Since you don’t have to ingest it, and you don’t have to take it when you’re not hurting, it’s got a very low commitment level.

Penetrex is one of those extraordinary products that seems to get amazing feedback from those that use it. It’s almost as if it’s been a well-kept secret, as it appears to still be a grassroots product that hasn’t hit mainstream awareness. Hopefully we’re doing our part to get the word out, because this is definitely something worth trying, not just because the price is right, but also because people are adamant that this works just like it says on the label.

We like that this isn’t just masking the pain, but actually going to work to help heal what’s wrong, and at the same time making it feel better. By taking painkillers and aspirin you aren’t doing anything to help your body, simply dulling the pain so you can get through the day or keep playing your sport. This is not good for the body and will only make the condition worse in the long term. By massaging this in at the location of the pain you are doing your body a favor and helping it heal itself.

Final Penetrex Review

We’re jumping on the bandwagon here and giving Penetrex our Thumbs Up review. This is one of those products that you knew was out there, but maybe you just hadn’t heard about it before. A solid track record of success, big claims but not outlandish, good customer service, a guarantee that never expires, and the sort of reviews and ratings that you wish every product had so you could make good purchasing decisions every time.

Our Recommendation
You won’t know if this will work for you and your specific condition until you give it a try. At this price point, and with so many people testifying that it works, and with an unconditional guarantee backing it up, the only thing stopping you from getting this is inaction. No one can order the product for you. Since some of the conditions that this treats can be pretty debilitating there’s no time for hesitation, because if this works for you it’s going to represent a serious upgrade in your quality of life.

What do you think? Does Penetrex work or not?


{ 39 comments… read them below or add one }

MYOMM September 7, 2012 at 6:28 pm

Even if they’re just ibuprofen or your regular aspirin, after 20 years of suffering with chronic pain I want to stop taking pain killers for good. I feel like I’m slowly killing my body by ingesting so much medicine and I feel so depressed every time I pop another pill for pain relief. I’m gonna trust your review as I always do and I tell you the amazon review doesn’t hurt either. I think I’ll finally be able to say goodbye to pain killers now. (Cross my fingers~).


Mux miars July 22, 2018 at 11:49 pm

Hello has this worked for you? I’ve got cubital tunnel syndrome, tennis elbow and carpal tunnel syndrome with many other associated shooting type pains numbness etc. Your answer may help me with my depressed life of pain

Thank you


chesapeakelady September 7, 2013 at 10:35 pm

I had a full knee replacement a year ago, and while I was in rehab I got plantar fasciitis in my left heel. What a mess! I Googled Penetrex, and saw claims that it helped not only that, but could be used on my knee as well. I bit the bullet and bought a jar. What a difference it made on my heel. I used it a couple of times a day for almost a month. I also got a gel insert for my shoe. Between the two of these, I got almost instant relief. Was so happy I bought another 2 jars and have been using this off and on for the last year. It also worked well on my knee area where the joint was replaced. Big difference on that as well. It’s been just a bit over a year for the replacement, and it’s time for another jar of the Penetrex. Don’t think I’m ever going to give this stuff up.


Jason April 26, 2014 at 4:08 am

This stuff did work great for my tendonitis in my elbow.
However, it’s been proven that most things aren’t able to go through skin, like vitamins etc. and that they are pointless. Leading me to think how much of this actually gets through to help?
My conclusion: NONE of it. I think the simple fact that you are literally massaging your problem area (3-4 times a day or whenever it hurts) is really the culprit here as to what is helping your pain.


Stephen Sadler, Ph.D. July 15, 2017 at 7:53 pm

Hi, Jason

Penetrex contains a natural compound, MSM, that’s used topically as a carrier agent. That’s how you can get topical compounds carried through the skin.
We could prove that to ourselves in labs by applying some to our skin. After a bit you would taste something like oysters with some sulphur. Anyway, that’s how Penetrex penetrates.


Joseph Ansorge July 12, 2015 at 8:10 am

I have epicondylitis, tennis elbow variety.

I tried this stuff, Penetrex, and it was absolutely useless.

Oh, did I mention it was ineffective and does not work?

Well, just saying.


Dan M September 29, 2016 at 7:57 pm

Joseph, thank you for taking the time to leave your comments. I’m curious, did you contact the company for your full refund? Forgive me if I sound like the ad. I’m a long term sufferer & have found some success with this. Does it do everything it claims including walking my dog? Probably not, but I’ve called them & found them very helpful.
Thank you Joseph, & I wish you and anyone else searching for relief the very best.
Dan M.


ramirl January 30, 2017 at 12:14 am

heloo, does this penetrex also cure muscle swelling?? Pliz I have a small swelling on my ear and I want try this cream.


Dana July 14, 2015 at 2:51 pm

I started using it several months ago on a very sore Achilles tendon. I used it three times a day for a week and I saw a big imorovement. I now use once every few days. I was very skeptical when I started, but I’m now a believer.


cinders August 11, 2015 at 12:32 am

I got this for my husband who had tennis elbow for 3-4 years and nothing helped. He used Penetrex for a couple weeks and it took it completely away.


Angie January 23, 2016 at 7:05 pm

many claim that it is just the massaging that helps and while i agree that massage is a help penetrex does work better than the creams that blister the skin and it beats taking oral pain relievers – using it for arthritis in my hands and and repetitive stress injuries in my legs -soak in a hot tub for 20 minutes, dry off and rub it in-it does work


Rose A May 14, 2016 at 6:32 am

I have chronic arthritis and you are right. Soak in a tub if you can and apply this stuff; it does work. It’s the only thing that has given me relief. Granted it did take almost the whole jar but to relieve this pain it was worth it.


Andy February 16, 2016 at 3:36 pm

I am 51 years old and was diagnosed with severe oesto-arthritus in my knee (developed after an old sports injury / meniscus tear). My Doctor finally recommended surgery when nothing I was trying worked. On a whim after reading Amazon reviews I decided to try Penetrex. 2 months later I can tell you I am happy with that decision. I started rubbing it in around my kneecap about 3 – 4 times per day and experienced almost immediate relief. After one week I was exercising again (low impact, bike & elliptical). The exercise helped even more. After two weeks I cancelled my pending surgery. Over the past month I have been exercising almost daily and playing golf again. I have no more swelling and have dropped Penetrex applications to twice per day (morning and night). Awesome product in my opinion. Best of all, no more limping around!!


Marilyn March 25, 2016 at 12:53 am

I have had knee pain for two months, so painful that I could barely move went back to the doctor Monday because pain had become extremely unbearable Dr scheduled steroid shots in both knees for next week..after leaving Dr office I went to store to get some kind of rub to ease the pain …I had never heard of penetrex and after reading label decided what the hell! I rubbed my knees with the cream when I got to my car ..what a relief!!! Got out of the car with hardly any pain have used cream for three days now three times a day..all I can say is Thanks! I’m going to start exercising again and I will cancel my appointment for steroid shots! Also I have purchased a second jar!


Jackie May 22, 2016 at 4:04 am

I just got my cream on 5/20/16 and I can already see a difference. I have planter fascists in both feet with heel spurs. It’s definitely is helping with the inflammation. My heel isn’t as swollen.


Dug September 6, 2016 at 8:47 pm

I have golfer’s elbow. Not from golf, but badminton. This is a very common problem in competitive badminton.

I use Penetrex as a massage gel – doing cross fiber massage to the flexor muscle group twice a day for about 5 minutes each massage. It works! but is it Penetrex or the massage?. Maybe both but using the two together about 75% of the pain and discomfort disappeared in about a week – not 100% better but well on the way.


Jayson s September 28, 2016 at 3:50 pm

I broke my neck 10 years ago and have had multiple fusion surgeries and now suffer from pain due to chronic inflammation in my cervical spine. I have used penetrex three to four times a week for the last two years and I have to say give me some level of relief. Takes the edge off my pain and allows me to get moving again where I can work through that painful episodes.


Nicole November 19, 2016 at 11:46 pm

Someone who can relate. 3 neck fusions (c5-t1) over a period of 3 years (2010-2013) and I still live in chronic pain. Inflammation in my cervical spine and right arm shoulder and hand like nobody’s business. My right hand is my life, being a painter. I found this cream last December on Amazon and while it didn’t work right away, it has taken the edge off. Now there are days that are much worse than others especially when I am constantly using that arm. I have been faithful to this cream regardless. I live on 2 Aleve every night and I hope one day to kick those (although I’m not sure about that being reality due to the chronic pain) but this cream sure has helped.


Jason November 3, 2016 at 5:18 am

Amazon reviewers are generally very good.
I bought Penetrex at Wal-Mart but only after a quick check of the reviews.
I have mild diabetic neuropathy in my feet, it helps slightly for that but is magical for elbow pain and even my tmj pain.


David Mullinax December 1, 2016 at 2:55 pm

I have some sort of Bursitis pain in my left shoulder and saw this cream on amazon when i was purchasing a shoulder brace. I was up all night with pain dreading the work day to follow. Well I ordered this Penetrex with my brace to try it out before i put the brace on. So far I have not had to use the brace since this stuff as taken away my pain and I can actually get sleep at night now. This is a miracle cream if you ask me !


Linda Hachey December 13, 2016 at 9:20 pm

After waking up 5-6 times a night in extreme pain and after taking 120mg morphine a day with Tylenol, it was as if I hadn’t taken anything, because nothing was easing the pain! Night after night, the knee pain was sickening and constant. So after reading the reviews on Amazon I purchased Penetrex.

ABSOLUTE RELIEF! This is a MIRACLE CREAM, and you don’t have to use a lot of it, just a dab takes my knee pain away, and for me, it’s practically instant relief. I couldn’t believe it and asked my husband who hurt his foot a few days ago to try it as well. He did, and was as shocked as I was, because his foot pain vanished! Thank you makers of PENETREX I never want to be out of your product. Ever!


vince January 2, 2017 at 10:41 pm

I am on my third jar and I absolutely love this product, had surgery on my right shoulder and chronic inflammation in my left shoulder, was very painful to work out at the gym, since finding penetrex ,I’ve been using it as recommended and the pain in my shoulders has decreased immensely! I’ve tried almost all the pain relieving products, nothing has worked as well as this.


Cheryl March 20, 2017 at 12:46 pm

I have been a Tiger Balm die hard for years…but recently it is not helping with sciatica…I started using Penetrex Sat., 18 Mar 2017…I have to say the results are much better than with Tiger Balm….I was really surprised….


Jill April 20, 2017 at 1:17 pm

This stuff DOES penetrate through the skin, and I can give you a scientific reason WHY: DMSO was developed in the 60’s as a mild ORGANIC industrial solvent; it is a by-product of the paper-making industry (turning trees into paper) . A QUICK internet search of DMSO [Dimethyl sulfoxide] finds ample proof that it not only penetrates the skin, but CARRIES OTHER MEDICATIONS WITH IT!
“The first quality that struck Dr. Jacob about the drug was its ability to pass through membranes, an ability that has been verified by numerous subsequent researchers.1 DMSO’s ability to do this varies proportionally with its strength–up to a 90 percent solution. From 70 percent to 90 percent has been found to be the most effective strength across the skin” “Use of DMSO in medicine dates from around 1963, when an Oregon Health & Science University Medical School team, headed by Stanley Jacob, discovered it could penetrate the skin and other membranes without damaging them and could carry other compounds into a biological system. In medicine, DMSO is predominantly used as a topical analgesic, a vehicle for topical application of pharmaceuticals, as an anti-inflammatory, and an antioxidant.[19] Because DMSO increases the rate of absorption of some compounds through organic tissues, including skin, it is used in some transdermal drug delivery systems. Its effect may be enhanced with the addition of EDTA. It is frequently compounded with antifungal medications, enabling them to penetrate not just skin but also toenails and fingernails.”


Stephen Sadler, Ph.D. July 15, 2017 at 8:02 pm

Note – Penetrex ingredients say MSM or MSM/DMSO2. MSM is related to DMSO, with the same carrier properties.


DJ January 27, 2018 at 2:54 pm

Hey Jill. Thanks for the little paper that you copied somewhere off the internet. First of all, Doctor Jacobs is a QUACK! just Google that before you copy some more BS. You might even find to learn there is NO scientific proof that DMSO works in double blind tests Secondly, Penetrex does NOT contain any DMSO. So where in the hell did you pull that information out of, Your Ass?


Fredso March 25, 2018 at 8:39 pm

Shut up, snowflake


Chip Akin April 24, 2017 at 8:43 pm

I’m having nerve pain from the removal of my little toe. Nothing seem to work hopefully this will!


Terry September 20, 2017 at 7:58 pm

I used Penetrex and it works as well as a compounded prescription medication with Diclofenac and it just a little less expansive. I used it for my back pain and I also sometimes use straight DMSO which works well also. DMSO works well if you add a smashed aspirin in the solution before you apply it. Penetrex is pretty amazing for an over the counter pain remedy for me and I will continue to used it.


Luka May 2, 2018 at 7:57 pm

Can this help with tennis elbow ? I am having tennis elbow for about 4 yeras. I was going to electronic tretmans and similar staff, but in gym i still feel a pain while i train. Can this reduce pain and help me lift more weights ?


Mahesh June 21, 2018 at 6:41 pm

I am using this product to cure golfer elbow from last one month. When I use it I feel about 90% pain/discomfort relief.
When I stop using it and start some straightening exercise my forearm/elbow discomfort start again. Overall I recommand this product. You may give it a try too.


Mr Eb August 24, 2018 at 2:15 pm

Use absorbing, originally for horses. Works the best, check the amazon reviews. Not kidding….


Donna September 24, 2018 at 3:26 am

I have cortisone injections in my knee every 4 months, need a knee replacement due to severe osteoarthritis, I have tried almost everything for relief with limited success. I am in constant discomfort so thought I would give penetrex a go. Saturday I applied it every 3hours, Sunday I took my grandchildren to movie world and while I was not completely pain free, I was able to give them a good time. Just bought 3 more 4oz jars. My opinion is its good stuff!


Andrea I Bell October 5, 2018 at 4:12 am

I’m a 45 year old woman and have been suffering from agonizing pain for the past 25 years (car accident – both legs shred to pieces). Over the years I have developed especially in my left ankle severe arthritis and I have used anything and everything one could buy over the counter. Icy Hot, Biofreeze, Blue Emu…you name it, I used it. I even gave the CBD, which seems to be the latest “It-thing” a try, and it did absolutely “nothing” for me. I’m always on the search for pain relieving creams, oils, etc. and stumbled over Penetrex and gave it a try. What can I say……It works, it really does.
It is the only thing that makes the pain go away. I use it 3-4 times a day and massage it in, needed or not, I put it on. I might have to say that massaging, stretching the effected area certainly helps but it would not, nor has it ever taken the pain away. I have done so with all the other products I have used over the years and it never gave me the results and relief that I get from using Penetrax. I give Penetrax 5 stars because for me it works and I haven’t been in so much pain which is a relief. Oh by the way they now also have the Roll-On which I prefer over the cream.


Linda melms January 5, 2019 at 9:12 am

I have found this product amazing does not burn or smell strong very happy


Blaine points February 19, 2019 at 7:18 am

Had shoulder pain for years from a car wreck tried many products with no success saw penetrex at Wal-Mart several time but figured just another product that wouldn’t work also kind of expensive but the next time I was at Wal-Mart I decided what the heck I would give it a try. Best thing I have ever done pain is so far about nintey percent gone and I’m sure will disappear completely soon. What a relief after all these years. Thanks so much for such a great product.


Rose March 29, 2019 at 3:33 am

I have had debilitating sciatic pain for months and have been in agony while waiting to get an MRI referral. Been using a TENS unit, painkillers, muscle relaxers, a chiropractor and every lidocaine product on the market. On a whim I bought Penetrex at Walmart and without a doubt, this is the best product I have ever used. From the very first day I had significant relief and honestly, I was shocked. I had low expectations because I thought with it being all natural, it wouldn’t do anything. I am so thankful I found this product and plan to never be without it again. I still need back surgery but until that gets set up, I have been able to part with every single other potential remedy I had been using. I’m so very thankful!!


Jim May 8, 2019 at 2:38 pm

For what it’s worth, I don’t believe a lot of what I see/read on the internet.

Recently, at 58, carpal tunnel reared it’s ugly head and started effecting my right hand. I’m in a very physical line of work and stress my hands daily. I typically go through a pair of work gloves a month. Steel work.

It got to the point that I would get zapped just reaching for something. There didn’t have to be any weight or stress behind it. I could lift an envelope and feel the electric shock in my arm.

In looking for a way to take my hand with KT tape, I stumbled onto Penetrex. If it weren’t for the lengthy list of happy customers, I’d have passed it by.

I will swear to God for you right now, the day I received it was the last day I ever felt that shock. No lie.

Rubbed it into my wrists and hands daily, sometimes twice daily if I remembered. Realized after a week I hadn’t suffered an ‘attack’. Kept waiting. Nothing. So far, never again.

I just logged on to purchase my second jar and thought I’d just chime in with the rest of the happy customers.

Next I’m going to travel up my arms to my elbows and shoulders to see what effect it has on them as I fall apart approaching 60.


Agazine Brown June 18, 2019 at 11:33 am

I have been using penetrex for about eight months. I recommended it to my son and daughter in-law and they love. I keep this cream handy all the time. Thank you for this cream.


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